dyslipidemia after kidney transplantation and correlation with cyclosporine level

Dyslipidemia After Kidney Transplantation and Correlation With Cyclosporine Level

BACKGROUND Dyslipidemia after kidney transplantation is a frequent finding and is multifactorial. Immunosuppressive agents such as cyclosporine (CsA) can cause hypercholesterolemia. OBJECTIVES As there were few reports with conflicting evidence on whether CsA related dyslipidemia is dose related and that CsA monitoring assays (trough level, C0, or two hour post dose level, C2) is a better pre...

dyslipidemia after kidney transplantation and correlation with cyclosporine level: a glimpse into the future

Dyslipidemia After Kidney Transplantation and Correlation With Cyclosporine Level: A Glimpse into the Future

I read with interest the article by Hosseini et al. recently published in the Nephro-Urology Monthly, titled “dyslipidemia after kidney transplantation and correlation with cyclosporine level”. They concluded that dyslipidemia is common finding after kidney transplantation and has no correlation with Cyclosporine level (1). Importantly, serum creatinine was the only risk factor for hypercholest...

Laboratory Monitoring of Cyclosporine Pre-dose Concentration (C0) After Kidney Transplantation in Isfahan

Background: Cyclosporine is the main immunosuppressive agent used in organ transplantation which leads to considerable improvement in graft survival.  The large inter- and intra- patient variability in cyclosporine pharmacokinetics coupled with the agent’s narrow therapeutic index and adverse effects necessitate therapeutic monitoring of cyclosporine blood levels. Objective: The aim of this stu...

NEUROLOGIC AND PSYCHOLOGIC COMPLICATIONS AFTER KIDNEY TRANSPLANTATION

Neurologic and psychologic complications are usually related to drug toxicity, infections or symptoms induced by deterioration of renal allograft function. Metabolic encephalopathy, hypertensive encephalopathy, cerebrovascular events, and new-onset seizures have all been reported in organ-transplant recipients. Infections can be caused by listeria, cryptococcus, nocardia, aspergillus and mu...

Correlation between urine macrophage migration inhibitory factor (MIF)/creatinine ratio and time after kidney transplantation

 Abstract  Background: Despite the long-standing association of macrophage migration inhibitory  factor (MIF) with delayed-type hypersensitivity response, the potential role  of MIF in chronic allograft nephropathy is unknown. The association between upregulation of MIF expression, macrophage and T cell infiltration and the severity of  chronic allograft nephropathy suggests that MIF may be an ...